Journal of Pathology Informatics Journal of Pathology Informatics
Contact us | Home | Login   |  Users Online: 275  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size 


SYMPOSIUM - 2ND NORDIC SYMPOSIUM ON DIGITAL PATHOLOGY
Year : 2015  |  Volume : 6  |  Issue : 1  |  Page : 6

Histopathology in 3D: From three-dimensional reconstruction to multi-stain and multi-modal analysis


1 School of Computing, University of Leeds; HeteroGenius Limited, Leeds, United Kingdom
2 University College London, Camden, United Kingdom
3 Mathematical Cell Physiology Facility, Max-Delbrück Center for Molecular Medicine, Berlin, Germany
4 Leeds Institute of Molecular Medicine, Leeds, United Kingdom
5 School of Mechanical Engineering, University of Leeds, Leeds, United Kingdom
6 School of Computing, University of Leeds, Leeds, United Kingdom
7 Leeds Institute of Molecular Medicine; Leeds Teaching Hospitals, NHS Trust, Leeds, United Kingdom

Correspondence Address:
Dr. Derek Magee
School of Computing, University of Leeds; HeteroGenius Limited, Leeds
United Kingdom
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2153-3539.151890

Rights and Permissions

Light microscopy applied to the domain of histopathology has traditionally been a two-dimensional imaging modality. Several authors, including the authors of this work, have extended the use of digital microscopy to three dimensions by stacking digital images of serial sections using image-based registration. In this paper, we give an overview of our approach, and of extensions to the approach to register multi-modal data sets such as sets of interleaved histopathology sections with different stains, and sets of histopathology images to radiology volumes with very different appearance. Our approach involves transforming dissimilar images into a multi-channel representation derived from co-occurrence statistics between roughly aligned images.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2504    
    Printed44    
    Emailed1    
    PDF Downloaded462    
    Comments [Add]    
    Cited by others 8    

Recommend this journal