Journal of Pathology Informatics Journal of Pathology Informatics
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REVIEW ARTICLE
Year : 2016  |  Volume : 7  |  Issue : 1  |  Page : 43

Computer-based image analysis in breast pathology


1 Image Optimisation and Perception, Discipline of Medical Radiation Sciences, University of Sydney, Australia
2 Image Optimisation and Perception, Discipline of Medical Radiation Sciences, University of Sydney, Australia; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Correspondence Address:
Ziba Gandomkar
Image Optimisation and Perception, Discipline of Medical Radiation Sciences, University of Sydney, Australia

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2153-3539.192814

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Whole slide imaging (WSI) has the potential to be utilized in telepathology, teleconsultation, quality assurance, clinical education, and digital image analysis to aid pathologists. In this paper, the potential added benefits of computer-assisted image analysis in breast pathology are reviewed and discussed. One of the major advantages of WSI systems is the possibility of doing computer-based image analysis on the digital slides. The purpose of computer-assisted analysis of breast virtual slides can be (i) segmentation of desired regions or objects such as diagnostically relevant areas, epithelial nuclei, lymphocyte cells, tubules, and mitotic figures, (ii) classification of breast slides based on breast cancer (BCa) grades, the invasive potential of tumors, or cancer subtypes, (iii) prognosis of BCa, or (iv) immunohistochemical quantification. While encouraging results have been achieved in this area, further progress is still required to make computer-based image analysis of breast virtual slides acceptable for clinical practice.


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