Journal of Pathology Informatics Journal of Pathology Informatics
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Year : 2017  |  Volume : 8  |  Issue : 1  |  Page : 36

Three-dimensional imaging and scanning: Current and future applications for pathology

1 3Scan, Inc., San Francisco, California, USA
2 Department of Pathology, University of Washington, Seattle, Washington, USA
3 Department of Pathology, Saint Barnabas Medical Center, Livingston, New Jersey, USA
4 Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA
5 Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Correspondence Address:
Navid Farahani
2122, Bryant Street, San Francisco, CA 94110
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpi.jpi_32_17

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Imaging is vital for the assessment of physiologic and phenotypic details. In the past, biomedical imaging was heavily reliant on analog, low-throughput methods, which would produce two-dimensional images. However, newer, digital, and high-throughput three-dimensional (3D) imaging methods, which rely on computer vision and computer graphics, are transforming the way biomedical professionals practice. 3D imaging has been useful in diagnostic, prognostic, and therapeutic decision-making for the medical and biomedical professions. Herein, we summarize current imaging methods that enable optimal 3D histopathologic reconstruction: Scanning, 3D scanning, and whole slide imaging. Briefly mentioned are emerging platforms, which combine robotics, sectioning, and imaging in their pursuit to digitize and automate the entire microscopy workflow. Finally, both current and emerging 3D imaging methods are discussed in relation to current and future applications within the context of pathology.

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