Journal of Pathology Informatics Journal of Pathology Informatics
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TECHNICAL NOTE
Year : 2018  |  Volume : 9  |  Issue : 1  |  Page : 13

Constant quest for quality: Digital cytopathology


1 Department of Pathology, School of Medical Sciences, The University of New South Wales, Sydney, NSW 2052; The Royal College of Pathologists of Australasia Quality Assurance Programs Pty Ltd, St Leonards, NSW 2065; The Royal College of Pathologists of Australasia, Surry Hills, NSW 2010, Australia
2 The Royal College of Pathologists of Australasia Quality Assurance Programs Pty Ltd, St Leonards, NSW 2065, Australia

Correspondence Address:
Simone L Van Es
Department of Pathology, School of Medical Sciences, The University of New South Wales, Sydney, NSW 2052
Australia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpi.jpi_6_18

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Background: Special consideration should be given when creating and selecting cytopathology specimens for digitization to maximize quality. Advances in scanning and viewing technology can also improve whole-slide imaging (WSI) output quality. Methods: Accumulated laboratory experience with digitization of glass cytopathology slides was collected. Results: This paper describes characteristics of a cytopathology glass slide that can reduce quality on resulting WSI. Important points in the glass cytopathology slide selection process, preparation, scanning, and WSI-editing process that will maximize the quality of the resulting acquired digital image are covered. The paper outlines scanning solutions which have potential to predict issues with a glass cytopathology slide before image acquisition, allowing for adjustment of the scanning approach. WSI viewing solutions that better simulate the traditional microscope experience are also discussed. Conclusion: In addition to taking advantage of technical advances, practical steps can taken to maximize quality of cytopathology WSI.


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