Journal of Pathology Informatics

TECHNICAL NOTE
Year
: 2011  |  Volume : 2  |  Issue : 1  |  Page : 52-

An open-source software program for performing Bonferroni and related corrections for multiple comparisons


Kyle Lesack1, Christopher Naugler2 
1 Faculty of Medicine, Bachelor of Health Sciences Program, Room G503, O'Brien Centre for the BHSc, 3330 Hospital Drive N.W. Calgary, Alberta T2N 4N1, 2, Canada
2 Departments of Pathology and Laboratory Medicine, University of Calgary and Calgary Laboratory Services, C414, Diagnostic and Scientific Centre, 9, 3535 Research Road NW, Calgary AB Canada T2L 2K8, Canada

Correspondence Address:
Christopher Naugler
Departments of Pathology and Laboratory Medicine, University of Calgary and Calgary Laboratory Services, C414, Diagnostic and Scientific Centre, 9, 3535 Research Road NW, Calgary AB Canada T2L 2K8
Canada

Increased type I error resulting from multiple statistical comparisons remains a common problem in the scientific literature. This may result in the reporting and promulgation of spurious findings. One approach to this problem is to correct groups of P-values for «DQ»family-wide significance«DQ» using a Bonferroni correction or the less conservative Bonferroni-Holm correction or to correct for the «DQ»false discovery rate«DQ» with a Benjamini-Hochberg correction. Although several solutions are available for performing this correction through commercially available software there are no widely available easy to use open source programs to perform these calculations. In this paper we present an open source program written in Python 3.2 that performs calculations for standard Bonferroni, Bonferroni-Holm and Benjamini-Hochberg corrections.


How to cite this article:
Lesack K, Naugler C. An open-source software program for performing Bonferroni and related corrections for multiple comparisons.J Pathol Inform 2011;2:52-52


How to cite this URL:
Lesack K, Naugler C. An open-source software program for performing Bonferroni and related corrections for multiple comparisons. J Pathol Inform [serial online] 2011 [cited 2019 Sep 19 ];2:52-52
Available from: http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2011;volume=2;issue=1;spage=52;epage=52;aulast=Lesack;type=0