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  Indian J Med Microbiol
 

Figure 7: Identification of colon cancer. In a digital H&E stained tissue section of colonic adenocarcinoma (panel a), a single ring vector was selected such that it exhibited high specificity and sensitivity toward malignant glands (panel b). An additional single ring vector was selected such that it exhibited high specificity and sensitivity toward intervening intestinal stroma (panel c). Using combinatorial Boolean predicate calculus, the gated stromal area was subtracted from the gated malignant epithelium in panel B, yielding a hybrid vector-selection construct, in which greater sensitivity and specificity for the foreground feature was realized (panel d) than would be possible with a single vector alone

Figure 7: Identification of colon cancer. In a digital H&E stained tissue section of colonic adenocarcinoma (panel a), a single ring vector was selected such that it exhibited high specificity and sensitivity toward malignant glands (panel b). An additional single ring vector was selected such that it exhibited high specificity and sensitivity toward intervening intestinal stroma (panel c). Using combinatorial Boolean predicate calculus, the gated stromal area was subtracted from the gated malignant epithelium in panel B, yielding a hybrid vector-selection construct, in which greater sensitivity and specificity for the foreground feature was realized (panel d) than would be possible with a single vector alone