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  Indian J Med Microbiol
 

Figure 4: Comparative Full-field optical coherence tomography (FFOCT) and H&E images of non-neoplastic lung with false positive diagnosis. (a, b) Images of non-neoplastic tissue with collapse of normal lung architecture. Boxed areas and insets show dense connective tissue where it is difficult to rule out presence of tumor. (c, d) Images of non-neoplastic tissue showing clusters of smoker's macrophages (boxed areas and insets) and thickened alveolar septa (arrows). Inset shows bright spots in the cytoplasm of the macrophages, which are likely to be tar (Scale bars for FFOCT: (a) 1 mm; (c) 0.5 mm. Inset in (a) 0.1 mm; inset in C: 0.05 mm H&E total magnifications: (b) ×40 and (d) ×100. Insets: (b, d) ×200)

Figure 4: Comparative Full-field optical coherence tomography (FFOCT) and H&E images of non-neoplastic lung with false positive diagnosis. (a, b) Images of non-neoplastic tissue with collapse of normal lung architecture. Boxed areas and insets show dense connective tissue where it is difficult to rule out presence of tumor. (c, d) Images of non-neoplastic tissue showing clusters of smoker's macrophages (boxed areas and insets) and thickened alveolar septa (arrows). Inset shows bright spots in the cytoplasm of the macrophages, which are likely to be tar (Scale bars for FFOCT: (a) 1 mm; (c) 0.5 mm. Inset in (a) 0.1 mm; inset in C: 0.05 mm H&E total magnifications: (b) ×40 and (d) ×100. Insets: (b, d) ×200)