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  Indian J Med Microbiol
 

Figure 2: Example of a major discrepant CLM/WSI case discussed in the case meeting. In this case, the differential diagnosis was between, ASC-US (WSI) and moderate dysplasia (CLM 3). Parabasal or squamous metaplastic cells are seen with enlarged nuclei (1½ to 2 times the size of an intermediate squamous cell nucleus). The nuclei show some irregularities and coarse granular chromatin distribution. The N/C ratio is disturbed, grooves are present in some nuclei. Consensus diagnosis was moderate dysplasia on the WSI. CLM: Conventional light microscopy, WSI: Whole-slide imaging, ASC-US: atypical squamous cells of undetermined significance

Figure 2: Example of a major discrepant CLM/WSI case discussed in the case meeting. In this case, the differential diagnosis was between, ASC-US (WSI) and moderate dysplasia (CLM 3). Parabasal or squamous metaplastic cells are seen with enlarged nuclei (1½ to 2 times the size of an intermediate squamous cell nucleus). The nuclei show some irregularities and coarse granular chromatin distribution. The N/C ratio is disturbed, grooves are present in some nuclei. Consensus diagnosis was moderate dysplasia on the WSI. CLM: Conventional light microscopy, WSI: Whole-slide imaging, ASC-US: atypical squamous cells of undetermined significance