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  Indian J Med Microbiol
 

Figure 5: Detailed comparison of real OOF to simulated OOF images. (a) An in-focus image of a lymphocyte, shown in grayscale to improve visibility of artifacts: particularly, grid-like artifacts from JPEG compression and Poisson noise from the sensor. (b) When synthetically generating OOF training examples, just applying Gaussian or Bokeh blurring alone smooths these artifacts. (c) Adding Poisson noise and (d) JPEG artifacts restores these artifacts, resulting in more realistic images. (e) An real OOF image of the same cell type for comparison. OOF: Out-of-focus; JPEG: Joint Photographic Experts Group

Figure 5: Detailed comparison of real OOF to simulated OOF images. (a) An in-focus image of a lymphocyte, shown in grayscale to improve visibility of artifacts: particularly, grid-like artifacts from JPEG compression and Poisson noise from the sensor. (b) When synthetically generating OOF training examples, just applying Gaussian or Bokeh blurring alone smooths these artifacts. (c) Adding Poisson noise and (d) JPEG artifacts restores these artifacts, resulting in more realistic images. (e) An real OOF image of the same cell type for comparison. OOF: Out-of-focus; JPEG: Joint Photographic Experts Group