Journal of Pathology Informatics Journal of Pathology Informatics
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Year : 2016  |  Volume : 7  |  Issue : 1  |  Page : 10

Comparison of the diagnostic utility of digital pathology systems for telemicrobiology

1 Department of Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA
2 Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232; Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, USA
3 Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA
4 Department of Pathology, ARUP Laboratories, University of Utah, Salt Lake City, Utah, USA

Correspondence Address:
Liron Pantanowitz
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2153-3539.177687

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Introduction: Telemicrobiology is a growing component of clinical microbiology informatics. However, few studies have been performed to assess the diagnostic utility of telemicroscopy systems in evaluating infectious agents. Objective: Evaluate multiple contemporary digital pathology platforms for use in diagnostic telemicrobiology. Materials and Methods: A mix of thirty cases that included viral, bacterial, fungal, and parasitological findings were evaluated by four experts using ×40 whole slide imaging (WSI) scans, ×83 oil-immersion WSI scans, ×100 oil-immersion WSI scans, digital photomicrographs, and glass slides. Results: The ×83 WSI, ×100 WSI, and photomicrograph interpretations were not significantly different in quality and accuracy when compared to glass slide interpretations. The ×40 WSI interpretations were of lower quality and were more likely to be incorrect when compared to glass slide interpretations. Conclusions: In this study, high magnification, oil-immersion digital pathology platforms are better suited to support telemicrobiology applications and yield interpretations on par with glass slide evaluations.

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