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Month wise articles
Figures next to the month indicate the number of articles in that month
2022
March
[
1
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January
[
10
]
2021
December
[
7
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November
[
9
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September
[
8
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August
[
2
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July
[
1
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June
[
4
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May
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3
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April
[
4
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March
[
7
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February
[
3
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January
[
6
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2020
December
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2
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November
[
5
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October
[
3
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September
[
2
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August
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8
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July
[
4
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June
[
2
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May
[
1
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April
[
3
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March
[
3
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February
[
6
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January
[
1
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2019
December
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6
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November
[
4
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September
[
4
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August
[
3
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July
[
6
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June
[
1
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May
[
2
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April
[
6
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March
[
3
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February
[
4
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January
[
2
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2018
December
[
10
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November
[
4
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October
[
3
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September
[
4
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August
[
1
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July
[
3
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June
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5
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May
[
4
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April
[
10
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March
[
2
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February
[
4
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2017
December
[
5
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November
[
4
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October
[
3
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September
[
9
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July
[
5
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June
[
2
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May
[
4
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April
[
6
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March
[
6
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February
[
7
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2016
December
[
7
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November
[
5
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October
[
3
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September
[
7
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August
[
1
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July
[
7
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May
[
8
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April
[
7
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March
[
4
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February
[
2
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January
[
5
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2015
November
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4
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October
[
5
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September
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5
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August
[
4
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July
[
3
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June
[
19
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May
[
5
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April
[
1
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March
[
5
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February
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9
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January
[
3
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2014
November
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2
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October
[
5
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September
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4
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August
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6
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July
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8
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June
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1
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May
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3
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March
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8
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February
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3
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January
[
4
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2013
December
[
5
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November
[
2
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October
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4
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September
[
4
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August
[
3
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July
[
3
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June
[
5
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May
[
7
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March
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18
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February
[
1
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January
[
1
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2012
December
[
6
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November
[
1
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October
[
4
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September
[
4
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August
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7
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July
[
2
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June
[
1
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May
[
2
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April
[
7
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March
[
6
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February
[
7
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January
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13
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2011
December
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3
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November
[
1
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October
[
7
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August
[
9
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July
[
3
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June
[
7
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May
[
3
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March
[
6
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February
[
8
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January
[
6
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2010
December
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4
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November
[
1
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October
[
6
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September
[
1
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August
[
6
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July
[
6
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May
[
5
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Technical Note:
A method for the interpretation of flow cytometry data using genetic algorithms
Cesar Angeletti
J Pathol Inform
2018, 9:16 (20 April 2018)
DOI
:10.4103/jpi.jpi_76_17
PMID
:29770255
Background:
Flow cytometry analysis is the method of choice for the differential diagnosis of hematologic disorders. It is typically performed by a trained hematopathologist through visual examination of bidimensional plots, making the analysis time-consuming and sometimes too subjective. Here, a pilot study applying genetic algorithms to flow cytometry data from normal and acute myeloid leukemia subjects is described.
Subjects and Methods:
Initially, Flow Cytometry Standard files from 316 normal and 43 acute myeloid leukemia subjects were transformed into multidimensional FITS image metafiles. Training was performed through introduction of FITS metafiles from 4 normal and 4 acute myeloid leukemia in the artificial intelligence system.
Results:
Two mathematical algorithms termed 018330 and 025886 were generated. When tested against a cohort of 312 normal and 39 acute myeloid leukemia subjects, both algorithms combined showed high discriminatory power with a receiver operating characteristic (ROC) curve of 0.912.
Conclusions:
The present results suggest that machine learning systems hold a great promise in the interpretation of hematological flow cytometry data.
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Letter:
Patient portal access to diagnostic test results
Beuy Joob, Viroj Wiwanitkit
J Pathol Inform
2018, 9:15 (20 April 2018)
DOI
:10.4103/jpi.jpi_13_18
PMID
:29770254
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Original Article:
Career paths of pathology informatics fellowship alumni
Joseph W Rudolf, Christopher A Garcia, Matthew G Hanna, Christopher L Williams, Ulysses G Balis, Liron Pantanowitz, J Mark Tuthill, John R Gilbertson
J Pathol Inform
2018, 9:14 (9 April 2018)
DOI
:10.4103/jpi.jpi_66_17
PMID
:29721362
Background:
The alumni of today's Pathology Informatics and Clinical Informatics fellowships fill diverse roles in academia, large health systems, and industry. The evolving training tracks and curriculum of Pathology Informatics fellowships have been well documented. However, less attention has been given to the posttraining experiences of graduates from informatics training programs. Here, we examine the career paths of subspecialty fellowship-trained pathology informaticians.
Methods:
Alumni from four Pathology Informatics fellowship training programs were contacted for their voluntary participation in the study. We analyzed various components of training, and the subsequent career paths of Pathology Informatics fellowship alumni using data extracted from alumni provided curriculum vitae.
Results:
Twenty-three out of twenty-seven alumni contacted contributed to the study. A majority had completed undergraduate study in science, technology, engineering, and math fields and combined track training in anatomic and clinical pathology. Approximately 30% (7/23) completed residency in a program with an in-house Pathology Informatics fellowship. Most completed additional fellowships (15/23) and many also completed advanced degrees (10/23). Common primary posttraining appointments included chief medical informatics officer (3/23), director of Pathology Informatics (10/23), informatics program director (2/23), and various roles in industry (3/23). Many alumni also provide clinical care in addition to their informatics roles (14/23). Pathology Informatics alumni serve on a variety of institutional committees, participate in national informatics organizations, contribute widely to scientific literature, and more than half (13/23) have obtained subspecialty certification in Clinical Informatics to date.
Conclusions:
Our analysis highlights several interesting phenomena related to the training and career trajectory of Pathology Informatics fellowship alumni. We note the long training track alumni complete in preparation for their careers. We believe flexible training pathways combining informatics and clinical training may help to alleviate the burden. We highlight the importance of in-house Pathology Informatics fellowships in promoting interest in informatics among residents. We also observe the many important leadership roles in academia, large community health systems, and industry available to early career alumni and believe this reflects a strong market for formally trained informaticians. We hope this analysis will be useful as we continue to develop the informatics fellowships to meet the future needs of our trainees and discipline.
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Technical Note:
Constant quest for quality: Digital cytopathology
Simone L Van Es, Janelle Greaves, Stephanie Gay, Jennifer Ross, Derek Holzhauser, Tony Badrick
J Pathol Inform
2018, 9:13 (9 April 2018)
DOI
:10.4103/jpi.jpi_6_18
PMID
:29721361
Background: Special consideration should be given when creating and selecting cytopathology specimens for digitization to maximize quality. Advances in scanning and viewing technology can also improve whole-slide imaging (WSI) output quality. Methods: Accumulated laboratory experience with digitization of glass cytopathology slides was collected. Results: This paper describes characteristics of a cytopathology glass slide that can reduce quality on resulting WSI. Important points in the glass cytopathology slide selection process, preparation, scanning, and WSI-editing process that will maximize the quality of the resulting acquired digital image are covered. The paper outlines scanning solutions which have potential to predict issues with a glass cytopathology slide before image acquisition, allowing for adjustment of the scanning approach. WSI viewing solutions that better simulate the traditional microscope experience are also discussed. Conclusion: In addition to taking advantage of technical advances, practical steps can taken to maximize quality of cytopathology WSI.
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View Point:
Psychological aspects of utilizing telecytology for rapid on-site adequacy assessments
Aparna Mahajan, Suzanne Selvaggi, Liron Pantanowitz
J Pathol Inform
2018, 9:12 (9 April 2018)
DOI
:10.4103/jpi.jpi_2_18
PMID
:29721360
Rapid On-Site Evaluation (ROSE) has been well documented in its ability to improve the diagnostic yield and accuracy of fine needle aspirations across many sites, resulting in better quality of patient management and a simultaneous reduction in treatment costs. Telecytology makes it possible for cytology laboratories to offer ROSE in a cost effective manner, whilst employing only a small number of trained cytopathologists to cover many sites from a single connected location. However, the adoption of telecytology for ROSE has been lackluster. We believe that this reluctance is not only due to barriers such as technology limitations and financial obstacles, but also due to overlooked psychological factors. This article discusses the unaddressed psychological considerations of telecytology for ROSE.
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Erratum:
Erratum: Preconceived stakeholders' attitude toward telepathology: Implications for successful implementation
J Pathol Inform
2018, 9:11 (2 April 2018)
DOI
:10.4103/2153-3539.228968
PMID
:29692429
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Technical Note:
Implementation of a mobile clinical decision support application to augment local antimicrobial stewardship
Brian M Hoff, Diana C Ford, Dilek Ince, Erika J Ernst, Daniel J Livorsi, Brett H Heintz, Vincent Masse, Michael J Brownlee, Bradley A Ford
J Pathol Inform
2018, 9:10 (2 April 2018)
DOI
:10.4103/jpi.jpi_77_17
PMID
:29692947
Background:
Medical applications for mobile devices allow clinicians to leverage microbiological data and standardized guidelines to treat patients with infectious diseases. We report the implementation of a mobile clinical decision support (CDS) application to augment local antimicrobial stewardship.
Methods:
We detail the implementation of our mobile CDS application over 20 months. Application utilization data were collected and evaluated using descriptive statistics to quantify the impact of our implementation.
Results:
Project initiation focused on engaging key stakeholders, developing a business case, and selecting a mobile platform. The preimplementation phase included content development, creation of a pathway for content approval within the hospital committee structure, engaging clinical leaders, and formatting the first version of the guide. Implementation involved a media campaign, staff education, and integration within the electronic medical record and hospital mobile devices. The postimplementation phase required ongoing quality improvement, revision of outdated content, and repeated staff education. The evaluation phase included a guide utilization analysis, reporting to hospital leadership, and sustainability and innovation planning. The mobile application was downloaded 3056 times and accessed 9259 times during the study period. The companion web viewer was accessed 8214 times.
Conclusions:
Successful implementation of a customizable mobile CDS tool enabled our team to expand beyond microbiological data to clinical diagnosis, treatment, and antimicrobial stewardship, broadening our influence on antimicrobial prescribing and incorporating utilization data to inspire new quality and safety initiatives. Further studies are needed to assess the impact on antimicrobial utilization, infection control measures, and patient care outcomes.
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Original Article:
Electronic p-Chip-based system for identification of glass slides and tissue cassettes in histopathology laboratories
Wlodek Mandecki, Jay Qian, Katie Gedzberg, Maryanne Gruda, Efrain Frank Rodriguez, Leslie Nesbitt, Michael Riben
J Pathol Inform
2018, 9:9 (2 April 2018)
DOI
:10.4103/jpi.jpi_64_17
PMID
:29692946
Background:
The tagging system is based on a small, electronic, wireless, laser-light-activated microtransponder named “p-Chip.” The p-Chip is a silicon integrated circuit, the size of which is 600 μm × 600 μm × 100 μm. Each p-Chip contains a unique identification code stored within its electronic memory that can be retrieved with a custom reader. These features allow the p-Chip to be used as an unobtrusive and scarcely noticeable ID tag on glass slides and tissue cassettes.
Methods:
The system is comprised of p-Chip-tagged sample carriers, a dedicated benchtop p-Chip ID reader that can accommodate both objects, and an additional reader (the Wand), with an adapter for reading IDs of glass slides stored vertically in drawers. On slides, p-Chips are attached with adhesive to the center of the short edge, and on cassettes – embedded directly into the plastic. ID readout is performed by bringing the reader to the proximity of the chip. Standard histopathology laboratory protocols were used for testing.
Results:
Very good ID reading efficiency was observed for both glass slides and cassettes. When processed slides are stored in vertical filing drawers, p-Chips remain readable without the need to remove them from the storage location, thereby improving the speed of searches in collections. On the cassettes, the ID continues to be readable through a thin layer of paraffin. Both slides and tissue cassettes can be read with the same reader, reducing the need for redundant equipment.
Conclusions:
The p-Chip is stable to all chemical challenges commonly used in the histopathology laboratory, tolerates temperature extremes, and remains durable in long-term storage. The technology is compatible with laboratory information management systems software systems. The p-Chip system is very well suited for identification of glass slides and cassettes in the histopathology laboratory.
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Brief Report:
Challenges in communication from referring clinicians to pathologists in the electronic health record era
Andrea Lynne Barbieri, Oluwole Fadare, Linda Fan, Hardeep Singh, Vinita Parkash
J Pathol Inform
2018, 9:8 (2 April 2018)
DOI
:10.4103/jpi.jpi_70_17
PMID
:29692945
We report on the role played by electronic health record inbox messages (EHRmsg) in a safety event involving pathology. Evolving socio-cultural norms led to the coopting of EHRmsg for alternate use and oversight of a clinician to pathologist request. We retrospectively examined EHR inbox messages to pathologists over a 3 month block. 36 messages from 22 pathologists were assessed. 26 pertained to patient care including requests for report corrections and additional testing. 88% of requests had gone unaddressed. Clinicians assumed that pathologists used EHRmsg as clinical care team members, however, pathologists rarely did. Communication gaps exist between primary clinicians and pathologists in the EHR era and they have potential to result in patient harm. Different sociocultural norms and practice patterns between specialties underlie some of the breakdowns. Health information technology implementation needs to proactively look for new sociotechnical failure modes to avoid patient harm from communication lapses.
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Letter:
The case for an entropic simian in your laboratory: The case for laboratory information system failure scenario testing in the live production environment
Christopher L Williams, David S McClintock, Ulysses G J Balis
J Pathol Inform
2018, 9:7 (2 April 2018)
DOI
:10.4103/jpi.jpi_96_16
PMID
:29692944
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© Journal of Pathology Informatics | Published by Wolters Kluwer -
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Online since 10
th
March, 2010