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Figure 7: Receiver operating characteristic curve using maximum nuclear size to classify lowgrade (Grades I and II) and highgrade tumors (Grades III and IV). The optimal operation point is at a maximum nuclear size of 12.0 μm, which gives a false positive rate of 0.2 and a true positive rate of 1.0. The area under the curve is 0.97, suggesting good sensitivity and specificity using nuclear size in the image analysis algorithm to classify lowgrade tumors from highgrade ones 
