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  Indian J Med Microbiol
 

Figure 1: (a) In vitro validation of the anti-pimonidazole antibody by immunocytochemical staining using LNCaP prostate cancer cells. (b) Immunohistochemical staining for pimonidazole, osteopontin (O), hypoxia-inducible factor 1-alpha (H), and glucose transporter member 1 (G), scale bars 2 mm and 100 μm. (c) Generation of oxygen supply maps. (d) Dot-wise comparisons of both oxygen supply maps (OHG vs. P) in one representative case. (e and f) Box plots with Spearman correlation coefficients and mutual information comparing pimonidazole with osteopontin (O), hypoxia-inducible factor 1-alpha (H), glucose transporter member 1 (G), and combinatory overlays for 15 patients

Figure 1: (a) <i>In vitro</i> validation of the anti-pimonidazole antibody by immunocytochemical staining using LNCaP prostate cancer cells. (b) Immunohistochemical staining for pimonidazole, osteopontin (O), hypoxia-inducible factor 1-alpha (H), and glucose transporter member 1 (G), scale bars 2 mm and 100 μm. (c) Generation of oxygen supply maps. (d) Dot-wise comparisons of both oxygen supply maps (OHG vs. P) in one representative case. (e and f) Box plots with Spearman correlation coefficients and mutual information comparing pimonidazole with osteopontin (O), hypoxia-inducible factor 1-alpha (H), glucose transporter member 1 (G), and combinatory overlays for 15 patients