Figure 5:Operation of three other semi-automatic tools. (a) The wand tool in CytoMine[24] is a single-click flood-fill from the point of the mouse cursor. The result is local, limited to an area near the mouse. (b) The wand tool in QuPath[25] is a click-and-drag flood-fill using a smoothing preprocessing. Updates are received in real time as the user drags. Results are local. (c) In Ilastik,[34] the user provides examples of each label by click-dragging. After a button click, the user sees the result of labeling the entire image, a global result
![Figure 5:Operation of three other semi-automatic tools. (a) The wand tool in CytoMine<sup>[24]</sup> is a single-click flood-fill from the point of the mouse cursor. The result is local, limited to an area near the mouse. (b) The wand tool in QuPath<sup>[25]</sup> is a click-and-drag flood-fill using a smoothing preprocessing. Updates are received in real time as the user drags. Results are local. (c) In Ilastik,<sup>[34]</sup> the user provides examples of each label by click-dragging. After a button click, the user sees the result of labeling the entire image, a global result](articles/2020/11/1/images/JPatholInform_2020_11_1_27_292720_f5.jpg)