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  Indian J Med Microbiol
 

Figure 1: Schematic diagram of ccRCC nuclear morphology analysis workflow. (a) on H and E image of WSI, the regions of interest (ccRCC tumor area) is selected by outlining. (b) Within the region of interest area, ccRCC cells (blue) are separated from non-ccRCC areas (orange). (c) Individual ccRCC cell nuclei were segmented. (d) ccRCC nuclear profile area was demonstrated in different sizes in color. (e) Numeric data from size and shape features from an individual level of nucleus was calculated from pixels of digitized images. ccRCC: Clear cell renal cell carcinoma, WSI: Whole-slide image, H&E: Hematoxylin and eosin

Figure 1: Schematic diagram of ccRCC nuclear morphology analysis workflow. (a) on H and E image of WSI, the regions of interest (ccRCC tumor area) is selected by outlining. (b) Within the region of interest area, ccRCC cells (blue) are separated from non-ccRCC areas (orange). (c) Individual ccRCC cell nuclei were segmented. (d) ccRCC nuclear profile area was demonstrated in different sizes in color. (e) Numeric data from size and shape features from an individual level of nucleus was calculated from pixels of digitized images. ccRCC: Clear cell renal cell carcinoma, WSI: Whole-slide image, H&E: Hematoxylin and eosin